Department of Physics, PA College of Pharmacy Mangalore, PACE

PA College

of PHARMACY

Pharmaceutical chemistry is a discipline at the intersection of chemistry and pharmacology involved in with design, synthesis and developing drug candidates.

Pharmaceutical Chemistry is an important discipline which links many scientific disciplines and allows for collaboration with researchers from other disciplines like biologists, toxicologists, pharmacologists, microbiologists and bio-pharmacists in developing new drugs.

Department of Pharmaceutical Chemistry imparts in-depth knowledge about all the chemical aspects of drugs and natural products, such as structure, synthesis, isolation and structural activity relationship with Pharmacological activity. The department is consists of all major branches of pharmaceutical chemistry starting from basic organic chemistry, inorganic chemistry, medicinal chemistry, analytical and phytochemistry.

Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Computer-aided drug design and new biotechnological approaches are opening new path in the field of medicinal chemistry.

The Department offers excellent infrastructure with sophisticated instruments and well equipped laboratories. Pharmaceutical chemists are involved in designing and synthesizing new drugs as well as evaluate those drugs which are already in the market. They have the responsibility of designing newer drugs with improved efficacy, safety and pharmacokinetic profiles. .Pharmaceutical chemists are involved developing stringent analytical methods to the product for ensuring purity and develop analytical methods that will be useful for toxicological and pharmacological investigations.

Vision & Mission

Vision Mission

Vision

To instill a training and research attitude in the individuals in the field of synthetic and analytical chemistry of drug discovery and development.

Mission

To offer a stable environment and promote a research atmosphere among the students & faculty.
To train faculty & students in a safer and more efficient way to design and synthesize drug molecules and create awareness about innovation in the drug discovery and development field.
To create an opportunity to upgrade the knowledge regarding the analytical and chemical aspects of drug development and develop professional and trained medicinal chemists.

Faculty

faculty

DR. Muhammad Mubeen

Associate Professor

Qualification :-M. Pharm (Pharmaceutical Chemistry), Ph.D

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DR. Muhammad Mubeen

Associate Professor

M. Pharm

Educational And Experience Details

Qualification :M. Pharm (Pharmaceutical Chemistry), Ph.D

Total Experience : 15 years.

Publication

Suvarna G. Kini, Vikas Garg, Sharada Prasanna, Revathi Rajappan and Muhammad Mubeen. Protein Kinases as Drug Targets in Human and Animal Diseases. Current Enzyme Inhibition, 2017, 13, 1-8
Muhammad Mubeen, Suvarna G. Kini and K. S. R. Pai. Design, synthesis, antioxidant and anticancer activity of novel pyrazole derivatives. Der Pharma Chemica, 2015, 7(2):215-223
Benu Kumari, Suvarna G Kini, Muhammad Mubeen. Synthesis, Molecular Docking and Biological Evaluation of Some Quinazolinone Analogs. Manipal Journal of Pharmaceutical Sciences, 2015
Pramod B. Kumar, Suvarna G. Kini and Muhammad Mubeen. Synthesis, Antimicrobial and Docking Studies of Novel Benzotriazole Derivatives. Int J Pharm Bio Sci 2014 April ; 5 (2) : (P) 35 – 42
Muhammad Mubeen, Suvarna G. Kini. A Review On: The Design and Development of EGFR Tyrosine Kinase Inhibitors in Cancer Therapy. International Journal of Therapeutic Applications, Volume 5, 2012, 29 – 37

Research Projects:

Design, Synthesis and Anticancer Activity of Novel Heterocyclic compounds as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.

Awards/Achievements:

First Prize for the poster presentation during the 4th National Conference of Society of Biological Scientists of India SOBSICON 2014 held from 18th -20th November, 2014 at Yenepoya University, Mangalore.

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Mr. Vijay Kumar Mareguddi

Assistant Professor

Qualification :-M.Pharm (Pharmaceutical Chemistry)

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Mr. Vijay Kumar Mareguddi

Assistant Professor

M. Pharm

Educational And Experience Details

Qualification :M.Pharm (Pharmaceutical Chemistry)

Total Experience : 4 years.

Publication List:

Joshi SD, S R Prem Kumar, Patil S, M Vijaykumar, Kulkarni VH, Aminabhavi TM et al. Chemical synthesis, molecular modelling and pharmacophore mapping of new pyrrole derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. J Sau Chem Soc.2019;28(9):1838-1863.

Research project

Synthesis And Antitubercular Activity of Some Nitrogen Containing Heterocycles.

Achievements/ Conference presentations:

Qualified GPAT 2016 with 1022 rank
Qualified NIPER 2016 with 887 rank

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S MAHEEN ABDUL RAHMAN

Assistant Professor

Qualification :M. Pharm. Pharmaceutical Chemistry

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S MAHEEN ABDUL RAHMAN

Assistant Professor

M. Pharm. Pharmaceutical Chemistry

Educational And Experience Details

Qualification :M. Pharm. Pharmaceutical Chemistry

Publication

S. Maheen Abdul Rahmana, Jasvinder Singh Bhattib , Suresh Tharejab , Vikramdeep Monga* Current development of 1,2,3-triazole derived potential antimalarial scaffolds Structure-activity relationship (SAR) and bioactive compounds, 2023. European Journal of Medicinal Chemistry (EJMC), IF: 7.088 (2023) DOI: https://doi.org/10.1016/j.ejmech.2023.115699

Research Projects:

In silco Identification of Newer Morpholine Appended 3,4-disubstituted Pyrrolidine- 2,5-dione using Molecular Docking, MD Simulation as Lysophosphatidyl Choline Acyl Transferase (LPCAT 1 and LPCAT 2) Inhibitors for the Treatment of Cancer.
In-Silico Design, Synthesis, a-amylase Inhibition Studies of Benzimidazole Derivatives as Antidiabetic Agents.

Industries visited and Hospital training:

Attended the training for manufacturing, packaging, and analysis of tablets, syrups, and injections at Tablets India Pharmaceutical Pvt. Ltd. Chennai.
Trained at Rajiv Gandhi General Government Hospital, Chennai as a Hospital Pharmacist.

Awards/Achievements:

Qualified Graduate Pharmacy Aptitude Test (GPAT) with 97.2903481 scores and 197 marks in 2021.
Qualified Central Universities- Common Entrance Exam (CU-CET) with a score of 160 in 2021.

Seminars/ Workshops:

Participated 71 st Indian Pharmaceutical Congress (IPC) program and Attended the National Level Quiz Competition Organized by Madras Medical College.
Participated NIPER PHARMACON-2022. In NIPER, Mohali, Punjab. International Conference on Recent Trends and Future Opportunities in Pharmaceuticals.
Participated 73rd Indian Pharmaceutical Congress (IPC) program and presented a poster titled as In-Silico Design, Synthesis, a-amylase Inhibition Studies of Benzimidazole Derivatives as Antidiabetic Agents.
Participated as a "Delegate" in the Five Days Workshop/Training on "Computer Driven Drug Design and Formulations Research" held on 20 th -24 th May 2024 Organized by Department of Pharmaceutical Chemistry, JSSCP, In Association with Schrödinger LLC, Bengaluru.

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Ajeesh V

Associate Professor

Qualification :M. Pharm (Pharmaceutical Chemistry)

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